Background:  Aminopeptidases comprise a family of enzymatic proteins that are widely distributed in both eukaryotes and prokaryotes and function to catalyze the removal of amino acids from the N-termini of proteins. Aminopeptidase P2, also known as XPNPEP2 (X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound), is a 674 amino acid lipid-anchored cell membrane protein that belongs to the pita bread fold family of peptidase proteins. Expressed in colon, lung, kidney, heart, liver, placenta and small intestine, Aminopeptidase P2 exists as a homotrimer that functions as a metalloprotease and plays a role in Bradykinin metabolism, as well as in inflammatory responses throughout the body. Aminopeptidase P2 binds manganese as a cofactor and is subject to heavy post-translational glycosylation.

Description: Rabbit polyclonal to Aminopeptidase P2

Immunogen: KLH conjugated synthetic peptide derived from Aminopeptidase P2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 76 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.