Background:  CASD1 (CAS1 domain containing 1) is a 797 amino acid multi-pass membrane protein that belongs to the CASD1 family. Sharing high homology with glyco-syltransferases, CASD1 contains 15 putative transmembrane domains and is encode y a gene that maps to human chromosome 7q21.3, a region as sociated with myoclonic dystonia. Chromosome 7 has been linked to osteogen-esis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwach-man-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, anunusal comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Description: Rabbit polyclonal to CASD1

Immunogen: KLH conjugated synthetic peptide derived from CASD1

Specificity:  ·Reacts with Human, Mouse, Pig, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 92 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.