Background:  Kindlin-1, also called Kindlerin or Unc-112-related protein 1 (URP1), is a 677 amino acid member of the kindlin family involved in cell adhesion. Kindlin-1 interacts with the cytoplasmic domain of Integrin β1 and Integrin β3. Kindlin-1 is expressed in the cytoplasm, in cell junctions and in focal adhesions of brain, kidney, colon, skeletal muscle, adrenal gland, prostate and placenta.Kindlin-3, also known as FERMT3 (fermitin family homolog 3), URP2, KIND3, MIG-2, MIG2B or URP2, is a 667 amino acid protein that localizes to both the cell membrane and the cytoplasm and contains one PH domain and one FERM domain. Expressed at high levels in lymph node tissue and at lower levels in spleen, thymus, stomach, placenta, lung, testis and small intestine, Kindlin-3 is thought to be involved in cell adhesion events and may play a role in apoptosis.

Description: Rabbit polyclonal to Kindlin

Immunogen: KLH conjugated synthetic peptide derived from Kindlin

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 77 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.