Background: The Golgi apparatus is an organelle that plays an essential role in the modification and sorting of proteins that are exported from the endoplasmic reticulum (ER). GOLPH4 is a 696 amino acid single-pass type II membrane protein that localizes to the Golgi stack membrane and the cis and medial Golgi cisternae. One of many Golgi-resident proteins, GOLPH4 mediates protein trafficking along the late endosome-bypass pathway, thereby regulating protein transport from the early endosome to the Golgi. GOLPH4 has a large C-terminal luminal domain with potential N- and O-glycosylation sites, as well as a short N-terminal tail with a phosphorylation and myristoylation site.
Description: Rabbit polyclonal to GOLPH4
Immunogen: KLH conjugated synthetic peptide derived from GOLPH4
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 82 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.