Background:  HERC3 (Hect domain and RLD 3) belongs to the HERC family of ubiquitin ligases which contain a HECT domain and at least 1 RCC1-like domain (RLD). E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. The RLD domain is predicted to act as a guanine nucleotide exchange factor for small G proteins.

Description: Rabbit polyclonal to HERC3

Immunogen: KLH conjugated synthetic peptide derived from HERC3

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 117 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.