Background:  GPR62 (probable G protein-coupled receptor 62, hGPCR8) is a 368 amino acid protein encoded by the human GPR62 gene. GPR62 is an orphan receptor member of the G protein-coupled receptor 1 family. G protein-coupled receptors (GPCRs or GPRs) contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Key roles for G protein-coupled receptors include control of protein maturation and cell surface delivery and providing the correct framework for interactions with both heterotrimeric G proteins and arrestins to allow signal generation and its termination. GPR62 is expressed in brain tissue, most notably the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus.

Description: Rabbit polyclonal to GPR62

Immunogen: KLH conjugated synthetic peptide derived from GPR62

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 38 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.