Background: Human chorionic gonadotropin (hCG) is a peptide hormone produced in pregnancy, by the developing placenta and by the fertilized egg after implantation in the uterine wall. Its primary role is in the maintenance of the corpus luteum and causes it to secrete the hormone progesterone. Progesterone enriches the uterus with a thick lining of blood vessels and capillaries so that it can sustain the growing fetus. HCG is composed of two subunits, alpha and beta. The alpha subunit of HCG, however, is identical to the alpha subunit of luteinising hormone, thyroid stimulating hormone and follicle stimulating hormone. Serum human chorionic gonadotrophin testing is accurate 48 hour post conception. Urine human chorionic gonadotrophin testing is a popular method of home pregnancy determination as human chorionic gonadotrophin can be detected in urine.
Description: Rabbit polyclonal to hCG alpha 4
Immunogen: KLH conjugated synthetic peptide derived from hCG alpha 4
Specificity: ·Reacts with Human.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 10 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.