Background:  Protein Kinase A regulatory subunit I alpha belongs to the cAMP dependent kinase regulatory chain family. It contains 2 cyclic nucleotide-binding domains. The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules. Protein Kinase A regulatory subunit I alpha also interacts with RFC2; the complex may be involved in cell survival.

Description: Rabbit polyclonal to PRKAR1

Immunogen: KLH conjugated synthetic peptide derived from Human PRKAR1

Specificity:  ·Reacts with Human.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 43 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.