Background:  MOBKL2B (MOB1, Mps One Binder kinase activator-like 2B) is a 216 amino acid protein that is related to the yeast MOB1 protein. Yeast MOB1 binds Mps1, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Belonging to the MOB1/phocein family, MOBKL2B is suggested to regulate the activity of kinases. The gene encoding MOBKL2B is located on human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Chromosome 9 is considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype.

Description: Rabbit polyclonal to MOBKL2B

Immunogen: KLH conjugated synthetic peptide derived from MOBKL2B

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 25 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.