Background:  T1R1 (TR1, GPR70, gm148, taste receptor type 1 member 1, TAS1R1) is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. T1R1+3 responds to L-amino acids that are perceived as sweet. Multiple transcript variants encoding several different isoforms have been found for this gene. The T1R receptors are a family of taste-specific class C G protein-coupled receptors. PLCbeta2 and IP(3)R3 co-localize together with G(i2) as downstream components of two different types of taste receptors, T1R and T2R, in taste bud cells.

Description: Rabbit polyclonal to GPCR TAS1R1

Immunogen: KLH conjugated synthetic peptide derived from GPCR TAS1R1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 93 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry: 1/100;

·Immunofluorescence: 1/50-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.