Background:  A1BG (α-1B-glycoprotein), also known as A1B, ABG, GAB or HYST2477, is a 495 amino acid secreted glycoprotein that contains five immunoglobulin (Ig)-like V-type domains and belongs to the immunoglobulin superfamily. At an average concentration of 22mg/dl, A1BG is expressed in normal adult plasma and is thought to be involved in the regulation of cell behavior and cell recognition. In plasma, A1BG specifically binds to human CRISP-3, a member of the cysteine-rich secretory protein (CRISP) family comprised of evolutionarily conserved proteins which are believed to play a role in the innate immune system. Through its association with CRISP-3, A1BG is believed to function in protecting the body from the circulation of free CRISP-3, a circumstance with potentially harmful effects.

Description: Rabbit polyclonal to A1BG

Immunogen: KLH conjugated synthetic peptide derived from A1BG

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 54 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.