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Z DNA binding protein antibody, Z DNA结合蛋白抗体

 
编 号 PR-7487
产品名称 Z DNA binding protein antibody, Z DNA结合蛋白抗体
规 格 0.2ml
价 格 1980元
应 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

详细信息: 说明书下载

Background:  Left-handed Z-DNA is a higher energy form of the double helix. Proteins containing Za domains share a remarkable ability to bind specifically to Z-DNA and/or Z-RNA. ZBP1 (Z-DNA binding protein 1), also designated DLM-1, is a 429 amino acid protein that harbors two copies of the Za domain containing the Za motif at its N-terminus. ZBP1 is involved in host responses against cellular stresses, including tumorigenesis and viral infection. It is highly expressed in lymphatic tissues including leukocytes, lymph node, tonsil, bone marrow, spleen and, to a lesser extent, in thymus, lung and liver. There are five known isoforms of human ZBP1. The ZBP1 protein shares 47% and 46% sequence identity with the mouse and rat homologs, respectively. The mouse, rat, and human ZBP1 proteins all contain four conserved regions, two of which are homologous to the Z-DNA binding domains Za and Zb of the RNA editing enzyme ADAR1.

Description: Rabbit polyclonal to Z DNA binding protein

Immunogen: KLH conjugated synthetic peptide derived from Z DNA binding protein

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 46 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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