Background:  MGEA5, or meningioma expressed antigen 5, is a multifunctional enzyme containing two distinct enzymatic activities and two distinct active sites. MGEA5 was originally identified as a human hyaluronidase, which is immunogenic in meningioma patients. MGEA5 is an N-acetylglucosaminidase, cleaving GlcNAc but not GalNAc from glycopeptides. MGEA5 also possesses Histone acetyltransferase (HAT) activity and acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3.

Description: Rabbit polyclonal to MGEA5

Immunogen: KLH conjugated synthetic peptide derived from MGEA5

Specificity:  ·Reacts with Human, Mouse and Rat.      

·Isotype: IgG

Application:  ·Western blotting: 1/500-1000. Predicted Mol wt: 103 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/200;

·ELISA: 1/500;

· Optimal working dilutions must be determined by the end user.