Background:  ALDH1A2 belongs to the aldehyde dehydrogenase family of proteins. It is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida.

Description: Rabbit polyclonal to RALDH2

Immunogen: KLH conjugated synthetic peptide derived from RALDH2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG              

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 56 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-500;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.