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TIEG1 antibody, TGF-β诱导早期应答基因1抗体

 
编 号 PR-0421
产品名称 TIEG1 antibody, TGF-β诱导早期应答基因1抗体
规 格 0.2ml
价 格 1980元
应 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

详细信息: 说明书下载

Background:  KLF10 (Krueppel-like factor 10), also known as TIEG1, is a transcription factor that plays a role in the regulation of cell growth. It binds to the consensus sequence 5'-GGTGTG-3'. KLF10 plays a role in the response to TGFbeta (through the TGFbeta/Smad signalling pathway) and estrogen. In both cases, KLF10 induces or repressed gene transcription to enhance the TGFbeta/Smad signalling pathway, as well as other pathways, to regulate cell proliferation, differentiation and apoptosis. KLF10 has been shown to have a role in skeletal disease (osteopenia/osteoporosis), hypertrophic cardiomyopathy, and breast and prostate cancer.

Description: Rabbit polyclonal to TIEG1

Immunogen: KLH conjugated synthetic peptide derived from TIEG1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 53 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry: 1/100-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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