会员登陆 / 下载中心
当前位置:产品目录 > 抗体 >> 多克隆抗体
CTNNBIP1 antibody, β链接素相互作用蛋白1抗体

 
编 号 PR-0638
产品名称 CTNNBIP1 antibody, β链接素相互作用蛋白1抗体
规 格 0.2ml
价 格 1980元
应 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

详细信息: 说明书下载

Background:  CTNNBIP1 (Catenin, beta interacting protein 1) binds to beta-catenin and prevents the interaction between beta-catenin and TCF transcription factor family members. It is a negative regulator of the Wnt signaling pathway.ICAT interacts directly with β-catenin and interferes with the Wnt signaling pathway. Specifically, ICAT prevents the interaction of β-catenin with TCF-4 and inhibits βcatenin–TCF-4-mediated transactivation. The negative regulatory effect of ICAT on the Wnt signaling pathway appears to inhibit tumor cell proliferation. ICAT also induces G2 arrest followed by cell death in colorectal tumor cells. The ectopic induction of ICAT inhibits the expression of βIII-Tubulin and thus neuronal differentiation in embryonal carcinoma P19 cells. Structural characteristics of ICAT include a 3-helix bundle and a C-terminal tail.

Description: Rabbit polyclonal to CTNNBIP1

Immunogen: KLH conjugated synthetic peptide derived from CTNNBIP1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 9 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-200;

·Immunocytochemistry: 1/100;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

相关同类产品:

网站首页 | 公司动态 | 产品中心 | 定制服务 | 代理产品 | 技术专栏 | 客户留言 | 联系我们

Copyright @ 2011 All Rights Reserved 江苏镇江厚普生物科技有限公司 备案/许可证编号为:苏ICP备11043267号

地址:江苏省丹阳市吕城工业园 邮编:212300 电子邮箱:hopebiotech@163.com

订货电话:0511-86909515 传真:0511-86909515 访问量:20363322