Background:  RAC1 and RAC2 belong to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. They are plasma membrane-associated small GTPase which binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles.

Description: Rabbit polyclonal to RAC1+RAC2

Immunogen: KLH conjugated synthetic peptide derived from RAC1+RAC2

Specificity:  ·Reacts with Human, Mouse, Rabbit, Cow, Dog and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 21 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry: 1/200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.