Background:  IL-14 (high-molecular-weight B-cell growth factor or HMW-BCGF) is a 53kDa protein that plays a significant role in the rapid proliferation of aggressive B-cell type non-Hodgkin's lymphoma. IL-19 and IL-20 are IL-10-related cytokines. IL-19 is involved in melanoma differentiation, and IL-20 plays an essential role in epidermal function and psoriasis. Like other interleukin molecules, IL-21 is a small secreted molecule, and it has potent effects on lymphoid cells. IL-21 is most closely related to IL-2 and IL-15 and has a role in the proliferation and maturation of natural killer cell populations from bone marrow, in the proliferation of mature B-cell populations co-stimulated with anti-CD40, and in the proliferation of T cells co-stimulated with anti-CD3.

Description: Rabbit polyclonal to IL-19

Immunogen: KLH conjugated synthetic peptide derived from IL-19

Specificity:  ·Reacts with Human, Mouse and Rat.

.·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 20 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.