Background:  The NUMB and Numb-like genes are essential during nervous system development. Numb proteins function to maintain the self-renewal properties of all neural progenitor cells and could play similar roles in stem-cell maintenance in other tissues. Mice ablated for either NUMB or Numb-like in the nervous system are born normally, however deletion of both genes results in embryonic lethality.

Description: Rabbit polyclonal to NUMB

Immunogen: KLH conjugated synthetic peptide derived from NUMB

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 70 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.