会员登陆 / 下载中心
当前位置:产品目录 > 抗体 >> 多克隆抗体
RING2 antibody, 环指蛋白2抗体

 
编 号 PR-3230
产品名称 RING2 antibody, 环指蛋白2抗体
规 格 0.2ml
价 格 1980元
应 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

详细信息: 说明书下载

Background:  E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4. Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity.

Description: Rabbit polyclonal to RING2

Immunogen: KLH conjugated synthetic peptide derived from RING2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 38 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

相关同类产品:

网站首页 | 公司动态 | 产品中心 | 定制服务 | 代理产品 | 技术专栏 | 客户留言 | 联系我们

Copyright @ 2011 All Rights Reserved 江苏镇江厚普生物科技有限公司 备案/许可证编号为:苏ICP备11043267号

地址:江苏省丹阳市吕城工业园 邮编:212300 电子邮箱:hopebiotech@163.com

订货电话:0511-86909515 传真:0511-86909515 访问量:21178601