Background:  BMP11 is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. BMP11 is a secreted signal that acts globally to specify positional identity along the anterior/ posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.

Description: Rabbit polyclonal to BMP11

Immunogen: KLH conjugated synthetic peptide derived from BMP11

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 45 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-500;

·Immunocytochemistry: 1/100-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.