Background:  The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. They are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The specific functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. IL-34 (interleukin-34) is a 235 amino acid secreted mouse protein that belongs to the interleukin family of cytokines. Existing as a homodimer, IL-34 functions to promote the viability and differentiation of macrophages and monocytes and may also act as a ligand for c-Fms/CSF-1R, a colony-stimulating factor. Multiple alternatively spliced isoforms of IL-34 exist, all of which are encoded by a gene that maps to mouse chromosome 8.

Description: Rabbit polyclonal to IL34

Immunogen: KLH conjugated synthetic peptide derived from IL34

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 27 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.