Background: The F box, named after cyclin F in which it was originally observed, is an approximately 40-amino acid motif that binds SKP1. F-box proteins are components of modular E3 ubiquitin protein ligases called SCFs (SKP1, cullin, F-box proteins), which function in phosphorylation-dependent ubiquitination.
Description: Rabbit polyclonal to FbxO6
Immunogen: KLH conjugated synthetic peptide derived from FbxO6
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 34 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-200;
·Immunocytochemistry: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.