Background:  ACOX2 (acyl-Coenzyme A oxidase 2), also known as BCOX, BRCOX, THCCox or BRCACOX, is a 681 amino acid protein that localizes to the peroxisome and belongs to the acyl-CoA oxidase family. Expressed in heart, kidney, liver, brain, lung, pancreas, placenta and skeletal muscle, ACOX2 functions as a branched-chain acyl-CoA oxidase that is involved in the degradation of bile acid intermediates and long branched fatty acids in peroxisomes. ACOX2 exists as a heterodimer and uses FAD as a cofactor to catalyze oxidation reactions. Defects in the gene encoding ACOX2 may be associated with Zellweger syndrome, an extremely rare congenital disorder that is characterized by the absence of peroxisomes and usually results in death before six months of age.

Description: Rabbit polyclonal to ACOX2

Immunogen: KLH conjugated synthetic peptide derived from ACOX2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 77 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.