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CD20 antibody, CD20单抗

 
编 号 M-0383
产品名称 CD20 antibody, CD20单抗
规 格 0.2ml
价 格 1980元
应 用 IHC,ICC,IF
品 牌 Hopebiot

详细信息: 说明书下载

Background:  CD20 is a leukocyte surface antigen consisting of four transmembrane regions and cytoplasmic N- and C-termini. The cytoplasmic domain of CD20 contains multiple phosphorylation sites, leading to additional isoforms. CD20 is expressed primarily on B cells but has also been detected on both normal and neoplastic T cells. CD20 functions as a calcium-permeable cation channel, and it is known to accelerate the G0 to G1 progression induced by IGF-1. CD20 is activated by the IGF-1 receptor via the alpha subunits of the heterotrimeric G proteins. Activation of CD20 significantly increases DNA synthesis and is thought to involve basic helix-loop-helix leucine zipper transcription factors.

Description: Mouse monoclonal to CD20

Immunogen: KLH conjugated synthetic peptide derived from CD20

Specificity:  ·Recognizes Human CD20 in Immunohistochemiscal staining.

·Isotype: IgG

Application:  ·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Optimal working dilutions must be determined by the end user.

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