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p-STAT3(Ser727) antibody, 磷酸化信号转导和转录激活因子3抗体

 
编 号 PR-1273P
产品名称 p-STAT3(Ser727) antibody, 磷酸化信号转导和转录激活因子3抗体
规 格 0.1ml
价 格 1980元
应 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

详细信息: 说明书下载

Background:  Stat3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.

Description: Rabbit polyclonal to Stat3phospho-Ser727

Immunogen: A synthesized phosphopeptide derived from human Stat3 around the phosphorylation site of Ser727.

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 88 kDa;

·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-200;

·Immunocytochemistry: 1/100;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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