Kruppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the co-regulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Kruppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the Collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis. The human homolog is a transcription factor involved in haematopoietic differentiation. It binds to the CACCC box.
我公司新研发的KLF3(Kruppel样因子3)抗体已经通过检验测试，可以应用于蛋白印迹（WB），免疫组化（IHC），免疫细胞化学（ICC），酶联免疫吸附试验（ELISA），免疫沉淀（IP），免疫荧光（IF）实验。具体信息如下：
编号 产品名称
PR-1003， KLF3 Antibody
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镇江厚普生物科技有限公司销售部
2015-10-28