Moesin is a member of the ERM (Ezrin-Radixin-Moesin) protein family, which possesses structural and probably functional relationships; they function as plasma membrane-actin cytoskeleton linkers and participate in the formation of specialized domains of the plasma membrane and are all localized to the submembranous cytoskeleton. Moesin is widely expressed in different tissues in cells, where it is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signalling and for cell movement.
Moesin是细胞骨架与细胞膜之间的连接蛋白,对细胞膜区域的整合和稳定性起到结构和功能调控的作用.通过连接细胞骨架和细胞膜。Moesin对细胞黏附、形态、分化、运动等起到重要调节作用。膜突蛋白早先被鉴定为一种硫酸乙酰肝素的可能受体和细胞骨架的连接蛋白,能稳定细胞表面的微绒毛、丝足和层形足板。膜-细胞骨架连接蛋白的埃兹蛋白-根蛋白-膜突蛋白(ERM)家族的成员都具有与质膜和肌动蛋白细胞骨架分别相连的氨基端和羧基端结构域。
我公司新研发的Moesin(膜结构伸展刺突蛋白)抗体已经通过检验测试,可以应用于蛋白印迹(WB),免疫组化(IHC),免疫细胞化学(ICC),酶联免疫吸附试验(ELISA),免疫沉淀(IP),免疫荧光(IF)实验。具体信息如下:
编号 产品名称
PR-1014, Moesin Antibody
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镇江厚普生物科技有限公司销售部
2015-10-28