bNOS (nitric oxide synthase from brain) produces nitric oxide which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter. bNOS is an inhibitory transmitter for non-adrenergic and non cholinergic nerves in the colorectum. NOS is classified under three types: Type I NOS is found in neurons and is constitutively expressed and Ca2+/calmodulin dependent. It is called NOS-1, neuronal NOS (nNOS), brain NOS (bNOS), cerebral / constitutive / Ca2+ regulated NOS (cNOS). bNOS is present in skeletal muscles and its absence in Duchenne’s muscular dystrophy accounts for its symptoms of the disease. Type II NOS is 130kDa protein known as macrophage NOS (mNOS) or inducible NOS (iNOS). It is Ca2+/calmodulin independent and is expressed in activated macrophages and stimulated glial cells. Type III NOS is a 135kDa protein called endothelial NOS (eNOS).
一氧化氮合成酶-1催化生物体内一氧化氮（NO）生成的酶。分神经型一氧化氮合成的酶（nNOS or NOS1）、诱导型一氧化氮合成的酶（iNOS or NOS2）、内皮型一氧化氮合成的酶（eNOS or NOS3）。此抗体识别分子量为150kDa的神经型一氧化氮合成的酶。
我公司新研发的NOS1(氧化一氮合成酶)抗体已经通过检验测试，可以应用于蛋白印迹（WB），免疫组化（IHC），免疫细胞化学（ICC），酶联免疫吸附试验（ELISA），免疫沉淀（IP），免疫荧光（IF）实验。具体信息如下：
编号 产品名称
PR-1026， NOS1 Antibody
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镇江厚普生物科技有限公司销售部
2015-10-28