Background:  BTNL8 is a 500 amino acid single-pass type I membrane protein that belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and one Ig-like V-type (immunoglobulin-like) domain. Expressed as multiple alternatively spliced isoforms, BTNL8 is encoded by a gene which maps to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 comprises about 6% of human genomic DNA. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm on chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Description: Rabbit polyclonal to BTNL8

Immunogen: KLH conjugated synthetic peptide derived from BTNL8

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 57 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.