Background: TSARG6 (Testis spermatogenesis apoptosis-related gene 6 protein), also known as DnaJB13 (DnaJ homolog subfamily B member 13) or TSARG5, is a 316 amino acid member of the DnaJ/HSP 40 family of ATPase-stimulating proteins. Strongly expressed in testis and weakly expressed in liver, spleen, heart and lung, TSARG6 contains one J domain and is thought to be involved in inhibiting testis spermatogenesis apoptosis. The gene encoding TSARG6 contains eight exons and the TSARG6 protein shares 87% sequence identity with its mouse counterpart. In mice, this protein is implicated in assembly and stability of axoneme during sperm development. Three isoforms of TSARG6 exist due to alternative splicing events.
Description: Rabbit polyclonal to TSARG6
Immunogen: KLH conjugated synthetic peptide derived from TSARG6
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 36 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.