Background:  STELLA is a member of the developmental pluripotency-associated protein family thought to play a key role in embryonic germ cell development. Expressed highly in fetal ovary with lower expression found in the testis and thymus, STELLA contributes to germ cell differentiation and acts as a maternal factor regulating early embryogensis. In addition to contributing to normal embryonic development, STELLA is overexpressed in testicular germ cell tumors, indicating a possible role in tumor formation. The elevated levels of STELLA observed in carcinoma cells suggest that it may be a novel candidate for early cancer detection.

Description: Rabbit polyclonal to DPPA3

Immunogen: KLH conjugated synthetic peptide derived from DPPA3

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 18 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.