Background:  GPATCH2 (G patch domain-containing protein 2) is a 528 amino acid protein that contains one G-patch domain. GPATCH2 is overexpressed in breast cancer tissue, and may have a role in breast cancer cell growth. Existing as two alternatively spliced isoforms, the gene encoding GPATCH2 maps to human chromosome 1q41 and mouse chromosome 1 H5. Spanning around 260 million base pairs, chromosome 1 is the largest human chromosome and comprises 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Description: Rabbit polyclonal to GPATCH2

Immunogen: KLH conjugated synthetic peptide derived from GPATCH2

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 59 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry: 1/100;

·Immunofluorescence: 1/50-200;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.